68 research outputs found
Alzheimer's disease pathology and the unfolded protein response : Prospective pathways and therapeutic targets
The authors would like to thank Alzheimer's Research UK (Grant refs: ARUK-PPG2014A-21 and ARUK-NSG2015-1 to BP and DK) who have provided support for relevant projects leading to this review.Peer reviewedPostprin
Knock-in of Human BACE1 Cleaves Murine APP and Reiterates Alzheimer-like PhenoTypes
Footnotes We thank Roemex and the College for Life Science and Medicine at the University of Aberdeen for their generous support. The authors declare no competing financial interests.Peer reviewedPublisher PD
Assessing the strength of directed influences among neural signals : An approach to noisy data
Acknowledgements This work was supported by the German Science Foundation (Ti315/4-2), the German Federal Ministry of Education and Research (BMBF grant 01GQ0420), and the Excellence Initiative of the German Federal and State Governments. B.S. is indebted to the Kosterlitz Centre for the financial support of this research project.Peer reviewedPreprin
Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline
Acknowledgments We would like to gratefully acknowledge all donors and their families for the tissue provided for this study. Human tissue samples were supplied by the Brains for Dementia Research programme, jointly funded by Alzheimer’s Research UK, the Alzheimer’s Society and the Medical Research Council, and sourced from the MRC London Neurodegenerative Diseases Brain Bank, the Manchester Brain Bank, the South West Dementia Brain Bank (SWDBB), the Newcastle Brain Tissue Resource and the Oxford Brain Bank. The Newcastle Brain Tissue Resource and Oxford Brain Bank are also supported by the National Institute for Health Research (NIHR) Units. The South West Dementia Brain Bank (SWDBB) receives additional support from BRACE (Bristol Research into Alzheimer’s and Care of the Elderly). Alz-50, CP13, MC-1 and PHF-1 antibodies were gifted from Dr. Peter Davies and brain lystates from BACE1−/−mice were obtained from Prof Mike Ashford. The work presented here was funded by Alzheimer’s Research UK (Grant refs: ARUKPPG2014A-21 and ARUK-NSG2015-1 to BP and DK and NIH/NIA grants NIH/NINDS R01 NS082730 and R01 AG044372 to NK)Peer reviewedPublisher PD
Effects of dietary restriction on metabolic and cognitive health
M. S. M. is a recipient of the Elphinstone Scholarship of the University of Aberdeen as well as Institute of Medical Sciences postdoctoral studentship. Work in B. P. and M. D. laboratories is funded by Alzheimer's Research UK, British Heart Foundation and Diabetes UK. Tenovus Scotland and BBSRC DTP studentship funded the published work on methionine restriction in M. D. laboratory.Peer reviewedPostprin
Delirium screening in the intensive care unit using emerging QEEG techniques : A pilot study
This work was supported by an Alzheimer’s Society grant (project grant number AS-PG-14-039 to BP) and a British Journal of Anaesthesia / Royal College of Anaesthetists funded John Snow Anaesthesia iBSc Award (to AH).Peer reviewedPublisher PD
Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology
Peer reviewedPostprin
How stra(i)nge are your controls? : A comparative analysis of metabolic phenotypes in commonly used C57BL/6 substrains
Open Access via the PLOS Agreement Funding: The authors received no specific funding for this work.Peer reviewedPublisher PD
Brain region–specific lipid alterations in the PLB4 hBACE1 knock-in mouse model of Alzheimer’s disease
We are grateful to the Alzheimer’s Society Scottish Doctoral Training Centre and the RS Macdonald Trust Transition Fund for funding the research presented.Peer reviewedPublisher PD
Of mice and motion : Behavioural-EEG phenotyping of Alzheimer’s disease mouse models
This work was supported by the Alzheimer’s Society [project grant number AS-PG-14-039] to BP and GR.Peer reviewedPostprin
- …